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PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

GSK-3-targeting fisetin promotes melanogenesis in B16F10 melanoma cells and Zebrafish larvae through -catenin activation

Its fatty acid modification (the C20 diacid) adds some bulk and hydrophobic character that can promote aggregation at elevated temperatures, but the overall stability profile is manageable with basic refrigeration practices